Publications

@article{Fonkeu2019_mRNA,

title = {How mRNA Localization and Protein Synthesis Sites Influence Dendritic Protein Distribution and Dynamics},

author = {Yombe Fonkeu and Nataliya Kraynyukova and Anne-Sophie Hafner and F Sartori and E. M. Schuman and Tatjana Tchumatchenko},

year  = {2019},

date = {2019-01-01},

journal = {Neuron},

volume = {103},

number = {5},

pages = {1109–1122},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Herfurth2019_info,

title = {Information transmission of mean and variance coding in integrate-and-fire neurons},

author = {T Herfurth and Tatjana Tchumatchenko},

year  = {2019},

date = {2019-01-01},

journal = {Physical Review E},

volume = {99},

pages = {032420},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Rose2018Experiencedependent,

title = {Experience-dependent plasticity in the lateral geniculate nucleus},

author = {Tobias Rose and Tobias Bonhoeffer},

url = {https://doi.org/10.1016/j.conb.2018.04.016},

doi = {10.1016/j.conb.2018.04.016},

year  = {2018},

date = {2018-12-01},

journal = {Current Opinion in Neurobiology},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Weiler2018Highyield,

title = {High-yield in vitro recordings from neurons functionally characterized in vivo},

author = {Simon Weiler and Joel Bauer and Mark Hübener and Tobias Bonhoeffer and Tobias Rose and Volker Scheuss},

url = {https://doi.org/10.1038/nprot.2018.026},

doi = {10.1038/nprot.2018.026},

year  = {2018},

date = {2018-05-01},

journal = {Nature Protocols},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Schmidt18_1409,

title = {Multi-scale account of the network structure of macaque visual cortex},

author = {Maximilian Schmidt and Rembrandt Bakker and Claus C. Hilgetag and Markus Diesmann and Sacha J. Albada},

url = {https://doi.org/10.1007/s00429-017-1554-4},

doi = {10.1007/s00429-017-1554-4},

issn = {1863-2661},

year  = {2018},

date = {2018-04-01},

journal = {Brain Struct Func},

volume = {223},

number = {3},

pages = {1409–1435},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kraynyukova2018_ssn,

title = {Stabilized supralinear network can give rise to bistable, oscillatory, and persistent activity},

author = {N Kraynyukova and Tatjana Tchumatchenko},

year  = {2018},

date = {2018-01-01},

journal = {Proceedings of the National Academy of Sciences (PNAS)},

volume = {115},

number = {14},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Schmidt18_e1006359,

title = {A multi-scale layer-resolved spiking network model of resting-state dynamics in macaque visual cortical areas},

author = {Maximilian Schmidt and Rembrandt Bakker and Kelly Shen and Gleb Bezgin and Markus Diesmann and Sacha J. Albada},

url = {https://doi.org/10.1371/journal.pcbi.1006359},

doi = {10.1371/journal.pcbi.1006359},

year  = {2018},

date = {2018-01-01},

urldate = {2018-01-01},

journal = {PLOS Comput Biol},

volume = {14},

number = {10},

pages = {e1006359},

publisher = {Public Library of Science},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gatto2018,

title = {Locomotion Control: Brainstem Circuits Satisfy the Need for Speed},

author = {Graziana Gatto and Martyn Goulding},

doi = {10.1016/j.cub.2018.01.068},

issn = {09609822},

year  = {2018},

date = {2018-01-01},

journal = {Current Biology},

volume = {28},

number = {6},

abstract = {Three new and closely complementary studies have defined the architecture of the circuits underlying the descending control of locomotion, identifying neurons that drive fast motor responses and those that seem to be specialised for exploratory behaviors.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Koch2017,

title = {RORβ Spinal Interneurons Gate Sensory Transmission during Locomotion to Secure a Fluid Walking Gait},

author = {Stephanie C. Koch and Marta Garcia Del Barrio and Antoine Dalet and Graziana Gatto and Thomas Günther and Jingming Zhang and Barbara Seidler and Dieter Saur and Roland Schüle and Martyn Goulding},

url = {https://linkinghub.elsevier.com/retrieve/pii/S0896627317310644},

doi = {10.1016/j.neuron.2017.11.011},

issn = {10974199},

year  = {2017},

date = {2017-12-01},

journal = {Neuron},

volume = {96},

number = {6},

pages = {1419–1431.e5},

abstract = {Animals depend on sensory feedback from mechanosensory afferents for the dynamic control of movement. This sensory feedback needs to be selectively modulated in a task- and context-dependent manner. Here, we show that inhibitory interneurons (INs) expressing the RORβ orphan nuclear receptor gate sensory feedback to the spinal motor system during walking and are required for the production of a fluid locomotor rhythm. Genetic manipulations that abrogate inhibitory RORβ IN function result in an ataxic gait characterized by exaggerated flexion movements and marked alterations to the step cycle. Inactivation of RORβ in inhibitory neurons leads to reduced presynaptic inhibition and changes to sensory-evoked reflexes, arguing that the RORβ inhibitory INs function to suppress the sensory transmission pathways that activate flexor motor reflexes and interfere with the ongoing locomotor program. Video Abstract [Figure presented] Koch et al. identify an inhibitory spinal circuit that is required for fluid rhythmic stepping movements. Inhibitory RORβ+ neurons in the spinal cord selectively gate proprioceptive transmission during locomotion by a presynaptic mechanism.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jaepel2017Lateral,

title = {Lateral geniculate neurons projecting to primary visual cortex show ocular dominance plasticity in adult mice},

author = {Juliane Jaepel and Mark Hübener and Tobias Bonhoeffer and Tobias Rose},

url = {https://doi.org/10.1038/s41593-017-0021-0},

doi = {10.1038/s41593-017-0021-0},

year  = {2017},

date = {2017-11-01},

journal = {Nature Neuroscience},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Rose2017Synapses,

title = {Synapses get together for vision},

author = {Tobias Rose and Mark Hübener},

url = {https://doi.org/10.1038/nature23098},

doi = {10.1038/nature23098},

year  = {2017},

date = {2017-07-01},

journal = {Nature},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Clopath2017Variance,

title = {Variance and invariance of neuronal long-term representations},

author = {Claudia Clopath and Tobias Bonhoeffer and Mark Hübener and Tobias Rose},

url = {https://doi.org/10.1098/rstb.2016.0161},

doi = {10.1098/rstb.2016.0161},

year  = {2017},

date = {2017-03-01},

journal = {Philosophical Transactions of the Royal Society B: Biological Sciences},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Keck2017Integrating,

title = {Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions},

author = {Tara Keck and Taro Toyoizumi and Lu Chen and Brent Doiron and Daniel E. Feldman and Kevin Fox and Wulfram Gerstner and Philip G. Haydon and Mark Hübener and Hey-Kyoung Lee and John E. Lisman and Tobias Rose and Frank Sengpiel and David Stellwagen and Michael P. Stryker and Gina G. Turrigiano and Mark C. Rossum},

url = {https://doi.org/10.1098/rstb.2016.0158},

doi = {10.1098/rstb.2016.0158},

year  = {2017},

date = {2017-03-01},

journal = {Philosophical Transactions of the Royal Society B: Biological Sciences},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Herfurth2017_linear,

title = {How linear response shaped models of neural circuits and the quest for alternatives},

author = {T Herfurth and Tatjana Tchumatchenko},

year  = {2017},

date = {2017-01-01},

journal = {Current Opinion in Neurobiology},

volume = {46},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Rose2016Cellspecific,

title = {Cell-specific restoration of stimulus preference after monocular deprivation in the visual cortex},

author = {Tobias Rose and Juliane Jaepel and Mark Hübener and Tobias Bonhoeffer},

url = {https://doi.org/10.1126/science.aad3358},

doi = {10.1126/science.aad3358},

year  = {2016},

date = {2016-06-01},

journal = {Science},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Dettner2016_spike,

title = {Temporal pairwise spike correlations fully capture single-neuron information},

author = {A Dettner and S Münzberg and Tatjana Tchumatchenko},

year  = {2016},

date = {2016-01-01},

journal = {Nature Communications},

volume = {7},

pages = {13805},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Albada15,

title = {Scalability of Asynchronous Networks Is Limited by One-to-One Mapping between Effective Connectivity and Correlations},

author = {Sacha J. Albada and Moritz Helias and Markus Diesmann},

editor = {Peter E. Latham},

url = {https://doi.org/10.1371/journal.pcbi.1004490},

doi = {10.1371/journal.pcbi.1004490},

year  = {2015},

date = {2015-01-01},

urldate = {2015-01-01},

journal = {PLOS Comput Biol},

volume = {11},

number = {9},

pages = {e1004490},

publisher = {Public Library of Science (PLoS)},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Rose2014Putting,

title = {Putting a finishing touch on GECIs},

author = {Tobias Rose and Pieter M. Goltstein and Ruben Portugues and Oliver Griesbeck},

url = {https://doi.org/10.3389/fnmol.2014.00088},

doi = {10.3389/fnmol.2014.00088},

year  = {2014},

date = {2014-11-01},

journal = {Frontiers in Molecular Neuroscience},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Marciniak2014Using,

title = {Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology},

author = {Anja Marciniak and Christian M Cohrs and Vasiliki Tsata and Julie A Chouinard and Claudia Selck and Julia Stertmann and Saskia Reichelt and Tobias Rose and Florian Ehehalt and Jürgen Weitz and Michele Solimena and Marjan Slak Rupnik and Stephan Speier},

url = {https://doi.org/10.1038/nprot.2014.195},

doi = {10.1038/nprot.2014.195},

year  = {2014},

date = {2014-11-01},

journal = {Nature Protocols},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gatto2014,

title = {EphA4 receptor shedding regulates spinal motor axon guidance},

author = {Graziana Gatto and Daniel Morales and Artur Kania and Rüdiger Klein},

doi = {10.1016/j.cub.2014.08.028},

issn = {09609822},

year  = {2014},

date = {2014-01-01},

journal = {Current Biology},

volume = {24},

number = {20},

pages = {2355–2365},

abstract = {Background: Proteolytic processing of axon guidance receptors modulates their expression and functions. Contact repulsion by membrane-associated ephrins and Eph receptors was proposed to be facilitated by ectodomain cleavage, but whether this phenomenon is required for axon guidance in vivo is unknown. Results: In support of established models, we find that cleavage of EphA4 promotes cell-cell and growth cone-cell detachment in vitro. Unexpectedly, however, a cleavage resistant isoform of EphA4 is as effective as a wild-type EphA4 in redirecting motor axons in limbs. Mice in which EphA4 cleavage is genetically abolished have motor axon guidance defects, suggesting an important role of EphA4 cleavage in nonneuronal tissues such as the limb mesenchyme target of spinal motor neurons. Indeed, we find that blocking EphA4 cleavage increases expression of full-length EphA4 in limb mesenchyme, which - via cis-attenuation - apparently reduces the effective concentration of ephrinAs capable of triggering EphA4 forward signaling in the motor axons. Conclusions: We propose that EphA4 cleavage is required to establish the concentration differential of active ephrins in the target tissue that is required for proper axon guidance. Our study reveals a novel mechanism to regulate guidance decision at an intermediate target based on the modulation of ligand availability by the proteolytic processing of the receptor. © 2014 Elsevier Ltd. All rights reserved..},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tchumatchenko2014_oscillations,

title = {Oscillations emerging from noise-driven steady state in networks with electrical synapses and subthreshold resonance},

author = {Tatjana Tchumatchenko and Claudia Clopath},

year  = {2014},

date = {2014-01-01},

journal = {Nature Communications},

volume = {5},

pages = {5512},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Rose2013Developmental,

title = {Developmental Refinement of Vesicle Cycling at Schaffer Collateral Synapses},

author = {Tobias Rose and Philipp Schoenenberger and Karel Jezek and Thomas G. Oertner},

url = {https://doi.org/10.1016/j.neuron.2013.01.021},

doi = {10.1016/j.neuron.2013.01.021},

year  = {2013},

date = {2013-03-01},

journal = {Neuron},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gatto2013,

title = {Protein Tyrosine Phosphatase Receptor Type O Inhibits Trigeminal Axon Growth and Branching by Repressing TrkB and Ret Signaling.},

author = {Graziana Gatto and Irina Dudanova and Philipp Suetterlin and Alun M Davies and Uwe Drescher and John L Bixby and Rüdiger Klein},

url = {http://www.ncbi.nlm.nih.gov/pubmed/23516305},

doi = {10.1523/JNEUROSCI.4707-12.2013},

issn = {1529-2401},

year  = {2013},

date = {2013-03-01},

journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},

volume = {33},

number = {12},

pages = {5399–410},

abstract = {Axonal branches of the trigeminal ganglion (TG) display characteristic growth and arborization patterns during development. Subsets of TG neurons express different receptors for growth factors, but these are unlikely to explain the unique patterns of axonal arborizations. Intrinsic modulators may restrict or enhance cellular responses to specific ligands and thereby contribute to the development of axon growth patterns. Protein tyrosine phosphatase receptor type O (PTPRO), which is required for Eph receptor-dependent retinotectal development in chick and for development of subsets of trunk sensory neurons in mouse, may be such an intrinsic modulator of TG neuron development. PTPRO is expressed mainly in TrkB-expressing (TrkB(+)) and Ret(+) mechanoreceptors within the TG during embryogenesis. In PTPRO mutant mice, subsets of TG neurons grow longer and more elaborate axonal branches. Cultured PTPRO(-/-) TG neurons display enhanced axonal outgrowth and branching in response to BDNF and GDNF compared with control neurons, indicating that PTPRO negatively controls the activity of BDNF/TrkB and GDNF/Ret signaling. Mouse PTPRO fails to regulate Eph signaling in retinocollicular development and in hindlimb motor axon guidance, suggesting that chick and mouse PTPRO have different substrate specificities. PTPRO has evolved to fine tune growth factor signaling in a cell-type-specific manner and to thereby increase the diversity of signaling output of a limited number of receptor tyrosine kinases to control the branch morphology of developing sensory neurons. The regulation of Eph receptor-mediated developmental processes by protein tyrosine phosphatases has diverged between chick and mouse.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tchumatchenko2013_energy,

title = {Energy-efficient encoding by shifting spikes in neocortical neurons},

author = {A Malyshev and Tatjana Tchumatchenko and S Volgushev and M Volgushev},

year  = {2013},

date = {2013-01-01},

journal = {European Journal of Neuroscience},

volume = {38},

number = {8},

pages = {1456–1464},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tchumatchenko2011_representation,

title = {Representation of dynamical stimuli in populations of threshold neurons},

author = {Tatjana Tchumatchenko and F Wolf and T Geisel and M Volgushev},

year  = {2011},

date = {2011-01-01},

journal = {PLoS Computational Biology},

volume = {7},

number = {2},

pages = {e1001059},

keywords = {},

pubstate = {published},

tppubtype = {article}

}